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Leinartaite L, Saraboji K, Nordlund A, Logan DT, Oliveberg M.
Folding catalysis by transient coordination of Zn2+ to the Cu ligands of the ALS-associated enzyme Cu/Zn superoxide dismutase 1.
J Am Chem Soc. 2010 Sep 29;132(38):13495-504.
PMID: 20822138 [PubMed - indexed for MEDLINE]
[Abstract] [J Am Chem Soc]

Oliveberg M.
Waltz, an exciting new move in amyloid prediction.
Nat Methods. 2010 Mar;7(3):187-8. No abstract available.
PMID: 20195250 [PubMed - indexed for MEDLINE]
[Abstract] [Nat Methods]

Byström R, Andersen PM, Gröbner G, Oliveberg M.
SOD1 mutations targeting surface hydrogen bonds promote amyotrophic lateral sclerosis without reducing apo-state stability.
J Biol Chem. 2010 Jun 18;285(25):19544-52. Epub 2010 Feb 26.
PMID: 20189984 [PubMed - indexed for MEDLINE]
[Abstract] [J Biol Chem]

Haglund E, Lind J, Oman T, Ohman A, Mäler L, Oliveberg M.
The HD-exchange motions of ribosomal protein S6 are insensitive to reversal of the protein-folding pathway.
Proc Natl Acad Sci U S A. 2009 Dec 22;106(51):21619-24. Epub 2009 Dec 4.
PMID: 19966220 [PubMed - indexed for MEDLINE]
[Abstract] [Proc Natl Acad Sci U S A]

Ohman A, Oman T, Oliveberg M.
Solution structures and backbone dynamics of the ribosomal protein S6 and its permutant P(54-55).
Protein Sci. 2010 Jan;19(1):183-9.
PMID: 19937661 [PubMed - indexed for MEDLINE]
[Abstract] [Protein Sci]

Gianni S, Brunori M, Jemth P, Oliveberg M, Zhang M.
Distinguishing between smooth and rough free energy barriers in protein folding.
Biochemistry. 2009 Dec 15;48(49):11825-30.
PMID: 19877713 [PubMed - indexed for MEDLINE]
[Abstract] [Biochemistry]

Teilum K, Smith MH, Schulz E, Christensen LC, Solomentsev G, Oliveberg M, Akke M.
Transient structural distortion of metal-free Cu/Zn superoxide dismutase triggers aberrant oligomerization.
Proc Natl Acad Sci U S A. 2009 Oct 27;106(43):18273-8. Epub 2009 Oct 14.
PMID: 19828437 [PubMed - indexed for MEDLINE]
[Abstract] [Proc Natl Acad Sci U S A]

Nordlund A, Leinartaite L, Saraboji K, Aisenbrey C, Gröbner G, Zetterström P, Danielsson J, Logan DT, Oliveberg M.
Functional features cause misfolding of the ALS-provoking enzyme SOD1.
Proc Natl Acad Sci U S A. 2009 Jun 16;106(24):9667-72. Epub 2009 Jun 2.
PMID: 19497878 [PubMed - indexed for MEDLINE]
[Abstract] [Proc Natl Acad Sci U S A]

Nordlund A, Oliveberg M.
SOD1-associated ALS: a promising system for elucidating the origin of protein-misfolding disease.
HFSP J. 2008 Dec;2(6):354-64. Epub 2008 Oct 14.
PMID: 19436494 [PubMed - in process]
[Abstract] [HFSP J]

Rousseau F, Schymkowitz J, Oliveberg M.
ALS precursor finally shaken into fibrils.
Proc Natl Acad Sci U S A. 2008 Dec 2;105(48):18649-50. Epub 2008 Nov 24. No abstract available.
PMID: 19033195 [PubMed - indexed for MEDLINE]
[Abstract] [Proc Natl Acad Sci U S A]

Haglund E, Lindberg MO, Oliveberg M.
Changes of protein folding pathways by circular permutation. Overlapping nuclei promote global cooperativity.
J Biol Chem. 2008 Oct 10;283(41):27904-15. Epub 2008 Jun 18.
PMID: 18562318 [PubMed - indexed for MEDLINE]
[Abstract] [J Biol Chem]

Zetterström P, Stewart HG, Bergemalm D, Jonsson PA, Graffmo KS, Andersen PM, Brännström T, Oliveberg M, Marklund SL.
Soluble misfolded subfractions of mutant superoxide dismutase-1s are enriched in spinal cords throughout life in murine ALS models.
Proc Natl Acad Sci U S A. 2007 Aug 28;104(35):14157-62. Epub 2007 Aug 21.
PMID: 17715066 [PubMed - indexed for MEDLINE]
[Abstract] [Proc Natl Acad Sci U S A]

Sandelin E, Nordlund A, Andersen PM, Marklund SS, Oliveberg M.
ALS-associated sod1 mutations preferentially reduce the proteins repulsive charge.
J Biol Chem. 2007 Jul 20;282(29):21230-6. Epub 2007 May 18.
PMID: 17513298 [PubMed - indexed for MEDLINE]
[Abstract] [J Biol Chem]

Lindberg MO, Oliveberg M.
Malleability of protein folding pathways: a simple reason for complex behaviour.
Curr Opin Struct Biol. 2007 Feb;17(1):21-9. Epub 2007 Jan 23. Review.
PMID: 17251003 [PubMed - indexed for MEDLINE]
[Abstract] [Curr Opin Struct Biol]

Hornberg A, Logan DT, Marklund SL, Oliveberg M.
The Coupling between Disulphide Status, Metallation and Dimer Interface Strength in Cu/Zn Superoxide Dismutase.
J Mol Biol. 2007 Jan 12;365(2):333-42. Epub 2006 Sep 23.
PMID: 17070542 [PubMed - indexed for MEDLINE]
[Abstract] [J Mol Biol]

Olofsson M, Hansson S, Hedberg L, Logan DT, Oliveberg M.
Folding of S6 Structures with Divergent Amino Acid Composition: Pathway Flexibility Within Partly Overlapping Foldons.
J Mol Biol. 2007 Jan 5;365(1):237-48. Epub 2006 Sep 12.
PMID: 17056063 [PubMed - indexed for MEDLINE]
[Abstract] [J Mol Biol]

Olofsson M, Kalinin S, Zdunek J, Oliveberg M, Johansson LB.
Tryptophan-BODIPY: a versatile donor-acceptor pair for probing generic changes of intraprotein distances.
Phys Chem Chem Phys. 2006 Jul 14;8(26):3130-40. Epub 2006 May 31.
PMID: 16804615 [PubMed - indexed for MEDLINE]
[Abstract] [Phys Chem Chem Phys]

Nordlund A, Oliveberg M.
Folding of Cu/Zn superoxide dismutase suggests structural hotspots for gain of neurotoxic function in ALS: parallels to precursors in amyloid disease.
Proc Natl Acad Sci U S A. 2006 Jul 5;103(27):10218-23. Epub 2006 Jun 23.
PMID: 16798882 [PubMed - indexed for MEDLINE]
[Abstract] [Proc Natl Acad Sci U S A] [Press Release]

Hubner IA, Lindberg M, Haglund E, Oliveberg M, Shakhnovich EI.
Common motifs and topological effects in the protein folding transition state.
J Mol Biol. 2006 Jun 16;359(4):1075-85. Epub 2006 Apr 24.
PMID: 16678203 [PubMed - indexed for MEDLINE]
[Abstract] [J Mol Biol] [Press Release]

Lindberg MO, Haglund E, Hubner IA, Shakhnovich EI, Oliveberg M.
Identification of the minimal protein-folding nucleus through loop-entropy perturbations.
Proc Natl Acad Sci U S A. 2006 Mar 14;103(11):4083-8. Epub 2006 Feb 27.
PMID: 16505376 [PubMed - indexed for MEDLINE]
[Abstract] [Proc Natl Acad Sci U S A] [Press Release]

Jonsson PA, Graffmo KS, Andersen PM, Brannstrom T, Lindberg M, Oliveberg M, Marklund SL.
Disulphide-reduced superoxide dismutase-1 in CNS of transgenic amyotrophic lateral sclerosis models.
Brain. 2006 Feb;129(Pt 2):451-64. Epub 2005 Dec 5.
PMID: 16330499 [PubMed - indexed for MEDLINE]
[Abstract] [Brain]

Oliveberg M, Shakhnovich EI.
Folding and binding: the conformational repertoire of proteins: folding, aggregation and structural recognition.
Curr Opin Struct Biol. 2006 Feb;16(1):68-70. Epub 2006 Jan 26. No abstract available.
PMID: 16443362 [PubMed - in process]
[Abstract] [Curr Opin Struct Biol]

Oliveberg M, Wolynes PG.
The experimental survey of protein-folding energy landscapes.
Q Rev Biophys. 2005 Aug;38(3):245-88. Epub 2006 Jun 19. Review.
PMID: 16780604 [PubMed - indexed for MEDLINE]
[Abstract] [Q Rev Biophys]

Lindberg MJ, Bystrom R, Boknas N, Andersen PM, Oliveberg M.
Systematically perturbed folding patterns of amyotrophic lateral sclerosis (ALS)-associated SOD1 mutants.
Proc Natl Acad Sci U S A. 2005 Jul 12;102(28):9754-9. Epub 2005 Jun 29.
PMID: 15987780 [PubMed - indexed for MEDLINE]
[Abstract] [Proc Natl Acad Sci U S A]

Shen T, Hofmann CP, Oliveberg M, Wolynes PG.
Scanning malleable transition state ensembles: comparing theory and experiment for folding protein U1A.
Biochemistry. 2005 May 3;44(17):6433-9.
PMID: 15850377 [PubMed - indexed for MEDLINE]
[Abstract] [Biochemistry]

Maxwell KL, Wildes D, Zarrine-Afsar A, De Los Rios MA, Brown AG, Friel CT, Hedberg L, Horng JC, Bona D, Miller EJ, Vallee-Belisle A, Main ER, Bemporad F, Qiu L, Teilum K, Vu ND, Edwards AM, Ruczinski I, Poulsen FM, Kragelund BB, Michnick SW, Chiti F, Bai Y, Hagen SJ, Serrano L, Oliveberg M, Raleigh DP, Wittung-Stafshede P, Radford SE, Jackson SE, Sosnick TR, Marqusee S, Davidson AR, Plaxco KW.
Protein folding: defining a "standard" set of experimental conditions and a preliminary kinetic data set of two-state proteins.
Protein Sci. 2005 Mar;14(3):602-16. Epub 2005 Feb 2.
PMID: 15689503 [PubMed - indexed for MEDLINE]
[Abstract] [Protein Sci]

Otzen DE, Oliveberg M.
Correspondence between anomalous m- and DeltaCp-values in protein folding.
Protein Sci. 2004 Dec;13(12):3253-63.
PMID: 15557266 [PubMed - indexed for MEDLINE]
[Abstract] [Protein Sci]

Lindberg MJ, Normark J, Holmgren A, Oliveberg M.
Folding of human superoxide dismutase: disulfide reduction prevents dimerization and produces marginally stable monomers.
Proc Natl Acad Sci U S A. 2004 Nov 9;101(45):15893-8. Epub 2004 Nov 2.
PMID: 15522970 [PubMed - indexed for MEDLINE]
[Abstract] [Proc Natl Acad Sci U S A]

Otzen DE, Miron S, Akke M, Oliveberg M.
Transient aggregation and stable dimerization induced by introducing an Alzheimer sequence into a water-soluble protein.
Biochemistry. 2004 Oct 19;43(41):12964-78.
PMID: 15476390 [PubMed - indexed for MEDLINE]
[Abstract] [Biochemistry]

Hubner IA, Oliveberg M, Shakhnovich EI.
Simulation, experiment, and evolution: understanding nucleation in protein S6 folding.
Proc Natl Acad Sci U S A. 2004 Jun 1;101(22):8354-9. Epub 2004 May 18.
PMID: 15150413 [PubMed - indexed for MEDLINE]
[Abstract] [Proc Natl Acad Sci U S A]

Hedberg L, Oliveberg M.
Scattered Hammond plots reveal second level of site-specific information in protein folding: phi' (beta++).
Proc Natl Acad Sci U S A. 2004 May 18;101(20):7606-11. Epub 2004 May 10.
PMID: 15136744 [PubMed - indexed for MEDLINE]
[Abstract] [Proc Natl Acad Sci U S A]

Otzen DE, Oliveberg M.
Transient formation of nano-crystalline structures during fibrillation of an Abeta-like peptide.
Protein Sci. 2004 May;13(5):1417-21.
PMID: 15096642 [PubMed - indexed for MEDLINE]
[Abstract] [Protein Sci]

Silow M, Oliveberg M.
High concentrations of viscogens decrease the protein folding rate constant by prematurely collapsing the coil.
J Mol Biol. 2003 Feb 7;326(1):263-71.
PMID: 12547208 [PubMed - indexed for MEDLINE]
[Abstract] [J Mol Biol]

Lindberg MJ, Tibell L, Oliveberg M.
Common denominator of Cu/Zn superoxide dismutase mutants associated with amyotrophic lateral sclerosis: decreased stability of the apo state.
Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16607-12. Epub 2002 Dec 13.
PMID: 12482932 [PubMed - indexed for MEDLINE]
[Abstract] [Proc Natl Acad Sci U S A]

Lindberg M, Tangrot J, Oliveberg M.
Complete change of the protein folding transition state upon circular permutation.
Nat Struct Biol. 2002 Nov;9(11):818-22.
PMID: 12368899 [PubMed - indexed for MEDLINE]
[Abstract] [Full Text] [Press Release]

Otzen DE, Oliveberg M.
Conformational plasticity in folding of the split beta-alpha-beta protein S6: evidence for burst-phase disruption of the native state.
J Mol Biol. 2002 Apr 5;317(4):613-27.
PMID: 11955013 [PubMed - indexed for MEDLINE]
[Abstract] [J Mol Biol]

Otzen DE, Oliveberg M.
Burst-phase expansion of native protein prior to global unfolding in SDS.
J Mol Biol. 2002 Feb 1;315(5):1231-40.
PMID: 11827490 [PubMed - indexed for MEDLINE]
[Abstract] [J Mol Biol]

Lindberg MO, Tangrot J, Otzen DE, Dolgikh DA, Finkelstein AV, Oliveberg M.
Folding of circular permutants with decreased contact order: general trend balanced by protein stability.
J Mol Biol. 2001 Dec 7;314(4):891-900.
PMID: 11734005 [PubMed - indexed for MEDLINE]
[Abstract] [J Mol Biol]

Otzen DE, Oliveberg M.
A simple way to measure protein refolding rates in water.
J Mol Biol. 2001 Oct 26;313(3):479-83.
PMID: 11676533 [PubMed - indexed for MEDLINE]
[Abstract] [J Mol Biol]

Oliveberg M.
Characterisation of the transition states for protein folding: towards a new level of mechanistic detail in protein engineering analysis.
Curr Opin Struct Biol. 2001 Feb;11(1):94-100. Review.
PMID: 11179897 [PubMed - indexed for MEDLINE]
[Abstract] [Curr Opin Struct Biol]

Otzen DE, Kristensen O, Oliveberg M.
Designed protein tetramer zipped together with a hydrophobic Alzheimer homology: a structural clue to amyloid assembly.
Proc Natl Acad Sci U S A. 2000 Aug 29;97(18):9907-12.
PMID: 10944185 [PubMed - indexed for MEDLINE]
[Abstract] [Proc Natl Acad Sci U S A]

Ternstrom T, Mayor U, Akke M, Oliveberg M.
From snapshot to movie: phi analysis of protein folding transition states taken one step further.
Proc Natl Acad Sci U S A. 1999 Dec 21;96(26):14854-9.
PMID: 10611302 [PubMed - indexed for MEDLINE]
[Abstract] [Proc Natl Acad Sci U S A]

Otzen DE, Oliveberg M.
Salt-induced detour through compact regions of the protein folding landscape
Proc Natl Acad Sci U S A. 1999 Oct 12;96(21):11746-51.
PMID: 10518521 [PubMed - as supplied by publisher]
[Abstract] [Proc Natl Acad Sci U S A]

Silow M, Tan YJ, Fersht AR, Oliveberg M.
Formation of short-lived protein aggregates directly from the coil in two-state folding. Biochemistry. 1999 Oct 5;38(40):13006-12.
PMID: 10529170 [PubMed - indexed for MEDLINE]
[Abstract] [Biochemistry]

Otzen DE, Kristensen O, Proctor M, Oliveberg M.
Structural changes in the transition state of protein folding: alternative interpretations of curved chevron plots.
Biochemistry. 1999 May 18;38(20):6499-511.
PMID: 10350468 [PubMed - indexed for MEDLINE]
[Abstract] [Biochemistry]

Oliveberg M, Tan YJ, Silow M, Fersht AR.
The changing nature of the protein folding transition state: implications for the shape of the free-energy profile for folding.
J Mol Biol. 1998 Apr 10;277(4):933-43.
PMID: 9545382 [PubMed - indexed for MEDLINE]
[Abstract] [J Mol Biol]

Dalby PA, Oliveberg M, Fersht AR.
Movement of the intermediate and rate determining transition state of barnase on the energy landscape with changing temperature.
Biochemistry. 1998 Mar 31;37(13):4674-9.
PMID: 9521788 [PubMed - indexed for MEDLINE]
[Abstract] [Biochemistry]

Dalby PA, Oliveberg M, Fersht AR.
Folding intermediates of wild-type and mutants of barnase. I. Use of phi-value analysis and m-values to probe the cooperative nature of the folding pre-equilibrium.
J Mol Biol. 1998 Feb 27;276(3):625-46.
PMID: 9551101 [PubMed - indexed for MEDLINE]
[Abstract] [J Mol Biol]

Silow M, Oliveberg M.
High-energy channeling in protein folding.
Biochemistry. 1997 Jun 24;36(25):7633-7.
PMID: 9201903 [PubMed - indexed for MEDLINE]
[Abstract] [Biochemistry]

Tan YJ, Oliveberg M, Otzen DE, Fersht AR.
The rate of isomerisation of peptidyl-proline bonds as a probe for interactions in the physiological denatured state of chymotrypsin inhibitor 2.
J Mol Biol. 1997 Jun 20;269(4):611-22.
PMID: 9217264 [PubMed - indexed for MEDLINE]
[Abstract] [J Mol Biol]

Silow M, Oliveberg M.
Transient aggregates in protein folding are easily mistaken for folding intermediates.
Proc Natl Acad Sci U S A. 1997 Jun 10;94(12):6084-6.
PMID: 9177173 [PubMed - indexed for MEDLINE]
[Abstract] [Proc Natl Acad Sci U S A]

Johnson CM, Oliveberg M, Clarke J, Fersht AR.
Thermodynamics of denaturation of mutants of barnase with disulfide crosslinks.
J Mol Biol. 1997 Apr 25;268(1):198-208.
PMID: 9149152 [PubMed - indexed for MEDLINE]
[Abstract] [J Mol Biol]

Tan YJ, Oliveberg M, Fersht AR.
Titration properties and thermodynamics of the transition state for folding: comparison of two-state and multi-state folding pathways.
J Mol Biol. 1996 Nov 29;264(2):377-89.
PMID: 8951383 [PubMed - indexed for MEDLINE]
[Abstract] [J Mol Biol]

Oliveberg M, Fersht AR.
New approach to the study of transient protein conformations: the formation of a semiburied salt link in the folding pathway of barnase.
Biochemistry. 1996 May 28;35(21):6795-805.
PMID: 8639631 [PubMed - indexed for MEDLINE]
[Abstract] [Biochemistry]

Oliveberg M, Fersht AR.
Thermodynamics of transient conformations in the folding pathway of barnase: reorganization of the folding intermediate at low pH.
Biochemistry. 1996 Feb 27;35(8):2738-49.
PMID: 8611580 [PubMed - indexed for MEDLINE]
[Abstract] [Biochemistry]

Oliveberg M, Fersht AR.
Formation of electrostatic interactions on the protein-folding pathway.
Biochemistry. 1996 Feb 27;35(8):2726-37.
PMID: 8611579 [PubMed - indexed for MEDLINE]
[Abstract] [Biochemistry]

Tan YJ, Oliveberg M, Davis B, Fersht AR.
Perturbed pKA-values in the denatured states of proteins.
J Mol Biol. 1995 Dec 15;254(5):980-92.
PMID: 7500365 [PubMed - indexed for MEDLINE]
[Abstract] [J Mol Biol]

Oliveberg M, Tan YJ, Fersht AR.
Negative activation enthalpies in the kinetics of protein folding.
Proc Natl Acad Sci U S A. 1995 Sep 12;92(19):8926-9.
PMID: 7568045 [PubMed - indexed for MEDLINE]
[Abstract] [Proc Natl Acad Sci U S A]

Oliveberg M, Arcus VL, Fersht AR.
pKA values of carboxyl groups in the native and denatured states of barnase: the pKA values of the denatured state are on average 0.4 units lower than those of model compounds.
Biochemistry. 1995 Jul 25;34(29):9424-33.
PMID: 7626612 [PubMed - indexed for MEDLINE]
[Abstract][Full Text Not Available Online]

Oliveberg M, Vuilleumier S, Fersht AR.
Thermodynamic study of the acid denaturation of barnase and its dependence on ionic strength: evidence for residual electrostatic interactions in the acid/thermally denatured state.
Biochemistry. 1994 Jul 26;33(29):8826-32.
PMID: 8038174 [PubMed - indexed for MEDLINE]
[Abstract][Full Text Not Available Online]

Hallen S, Oliveberg M, Brzezinski P.
Light-induced structural changes in cytochrome c oxidase. Measurements of electrogenic events and absorbance changes.
FEBS Lett. 1993 Mar 1;318(2):134-8.
PMID: 8382623 [PubMed - indexed for MEDLINE]
[Abstract] [FEBS Lett]

Oliveberg M, Malmstrom BG.
Reaction of dioxygen with cytochrome c oxidase reduced to different degrees: indications of a transient dioxygen complex with copper-B.
Biochemistry. 1992 Apr 14;31(14):3560-3.
PMID: 1314642 [PubMed - indexed for MEDLINE]
[Abstract][Full Text Not Available Online]

Oliveberg M, Malmstrom BG.
Internal electron transfer in cytochrome c oxidase: evidence for a rapid equilibrium between cytochrome a and the bimetallic site.
Biochemistry. 1991 Jul 23;30(29):7053-7.
PMID: 1649622 [PubMed - indexed for MEDLINE]
[Abstract][Full Text Not Available Online]

Oliveberg M, Hallen S, Nilsson T.
Uptake and release of protons during the reaction between cytochrome c oxidase and molecular oxygen: a flow-flash investigation.
Biochemistry. 1991 Jan 15;30(2):436-40.
PMID: 1846296 [PubMed - indexed for MEDLINE]
[Abstract][Full Text Not Available Online]

Oliveberg M, Brzezinski P, Malmstrom BG.
The effect of pH and temperature on the reaction of fully reduced and mixed-valence cytochrome c oxidase with dioxygen.
Biochim Biophys Acta. 1989 Dec 7;977(3):322-8.
PMID: 2556181 [PubMed - indexed for MEDLINE]
[Abstract][Full Text Not Available Online]